{"id":13097,"date":"2025-11-07T13:06:54","date_gmt":"2025-11-07T12:06:54","guid":{"rendered":"https:\/\/www.uni.lu\/lcsb-en\/?post_type=research-groups&#038;p=13097"},"modified":"2026-06-05T10:11:34","modified_gmt":"2026-06-05T08:11:34","slug":"publications","status":"publish","type":"research-groups","link":"https:\/\/www.uni.lu\/lcsb-en\/research-groups\/molecular-biophysics\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"<div class=\"section py-0 static\">\n<section class=\"py-0 wp-block-unilux-blocks-free-section section\"><div class=\"container xl:max-w-screen-xl\"><!-- SecondaryNavigationMirror --><div class=\"js-secondary-nav--sticky wp-block-unilux-blocks-secondary-navigation\" id=\"6bc66919-078e-4be4-8a56-a1589137e448\">\n    <nav id=\"secondary-navigation\" role=\"navigation\" aria-label=\"Secondary menu\" class=\"secondary-nav\">\n        <button class=\"secondary-nav__button btn btn-solid--primary w-full\" aria-expanded=\"false\" aria-controls=\"secondary-navigation__list\" title=\"The selected page is Overview\" type=\"button\">\n            <span class=\"btn__name mr-auto\">Overview<\/span>\n            <svg aria-hidden=\"true\" focusable=\"false\" class=\"icon icon-outline icon--xs\">\n                <use xlink:href=\"https:\/\/www.uni.lu\/wp-content\/themes\/unilux-theme\/assets\/images\/icons\/icons-outline.svg#icon--arrow-down\" \/>\n            <\/svg>\n        <\/button>\n\n        <ul id=\"secondary-navigation__list\" class=\"secondary-nav__list\">\n            <li class=\"secondary-nav__item\">\n    <a href=\"https:\/\/www.uni.lu\/lcsb-en\/research-groups\/molecular-biophysics\/\" target=\"\" rel=\"noreferrer noopener\" class=\"secondary-nav__link \">\n        <svg aria-hidden=\"true\" focusable=\"false\" class=\"icon icon-outline icon--xs\">\n            <use xlink:href=\"https:\/\/www.uni.lu\/wp-content\/themes\/unilux-theme\/assets\/images\/icons\/icons-outline.svg#icon--arrow-right\" \/>\n        <\/svg>\n        <span class=\"secondary-nav__name\">Overview<\/span>\n    <\/a>\n<\/li>\n<li class=\"secondary-nav__item\">\n    <a href=\"https:\/\/www.uni.lu\/lcsb-en\/research-groups\/molecular-biophysics\/research\/\" target=\"\" rel=\"noreferrer noopener\" class=\"secondary-nav__link \">\n        <svg aria-hidden=\"true\" focusable=\"false\" class=\"icon icon-outline icon--xs\">\n            <use xlink:href=\"https:\/\/www.uni.lu\/wp-content\/themes\/unilux-theme\/assets\/images\/icons\/icons-outline.svg#icon--arrow-right\" \/>\n        <\/svg>\n        <span class=\"secondary-nav__name\">Research<\/span>\n    <\/a>\n<\/li>\n<li class=\"secondary-nav__item\">\n    <a href=\"https:\/\/www.uni.lu\/lcsb-en\/research-groups\/molecular-biophysics\/publications\/\" target=\"\" rel=\"noreferrer noopener\" class=\"secondary-nav__link \">\n        <svg aria-hidden=\"true\" focusable=\"false\" class=\"icon icon-outline icon--xs\">\n            <use xlink:href=\"https:\/\/www.uni.lu\/wp-content\/themes\/unilux-theme\/assets\/images\/icons\/icons-outline.svg#icon--arrow-right\" \/>\n        <\/svg>\n        <span class=\"secondary-nav__name\">Publications<\/span>\n    <\/a>\n<\/li>\n<li class=\"secondary-nav__item\">\n    <a href=\"https:\/\/www.uni.lu\/lcsb-en\/research-groups\/molecular-biophysics\/people\/\" target=\"\" rel=\"noreferrer noopener\" class=\"secondary-nav__link \">\n        <svg aria-hidden=\"true\" focusable=\"false\" class=\"icon icon-outline icon--xs\">\n            <use xlink:href=\"https:\/\/www.uni.lu\/wp-content\/themes\/unilux-theme\/assets\/images\/icons\/icons-outline.svg#icon--arrow-right\" \/>\n        <\/svg>\n        <span class=\"secondary-nav__name\">People<\/span>\n    <\/a>\n<\/li>\n<li class=\"secondary-nav__item\">\n    <a href=\"https:\/\/www.uni.lu\/lcsb-en\/research-groups\/molecular-biophysics\/join-us\/\" target=\"\" rel=\"noreferrer noopener\" class=\"secondary-nav__link \">\n        <svg aria-hidden=\"true\" focusable=\"false\" class=\"icon icon-outline icon--xs\">\n            <use xlink:href=\"https:\/\/www.uni.lu\/wp-content\/themes\/unilux-theme\/assets\/images\/icons\/icons-outline.svg#icon--arrow-right\" \/>\n        <\/svg>\n        <span class=\"secondary-nav__name\">Join us<\/span>\n    <\/a>\n<\/li>\n        <\/ul>\n    <\/nav>\n<\/div>\n<!-- end SecondaryNavigationMirror --><\/div><\/section>\n\n\n\n<section class=\"wp-block-unilux-blocks-free-section section\"><div class=\"container xl:max-w-screen-xl\">\n<h2 class=\"has-text-align-left wp-block-unilux-blocks-heading\"        id=\"key-publications\"\n    >\nKey publications<\/h2>\n\n\n\n<ol class=\"ulux-list\">\n<li class=\"ulux-list-item\">Hu, J., Scheidt, T., Thacker, D., Axell, E., Stemme, E., \u0141api\u0144ska, U., Wennmalm, S., Meisl, G., Curk, S., Andreasen, M., Vendruscolo, M., Arosio, P., \u0160ari\u0107, A., Schmit, J. D., Knowles, T. P. J., Sparr, E., Linse, S., Michaels, T. C. T., Dear, A. J. (2026). Structural defects in amyloid-\u03b2 fibrils drive secondary nucleation. Nat Commun.<\/li>\n\n\n\n<li class=\"ulux-list-item\">*Yu, M., *Gruzinov, A., *Ruan, H., *Scheidt, T., Chowdhury, A., Giofre, S., Mohammed, A., Caria, J., Sauter, P. F., Svergun, D. &amp; Lemke, E. A. (2024) A genetically encoded anomalous SAXS ruler to probe the dimensions of intrinsically disordered proteins. Accepted in Proc. Natl. Acad. Sci. U.S.A.<\/li>\n\n\n\n<li class=\"ulux-list-item\">*Brzezinski, M., Argudo, P. G., Scheidt, T., Yu, M., Lemke, E. A., Michels, J. J. &amp; Parekh, S. H. (2025) Protein specific crowding accelerates aging in protein condensates. Biomacromolecules 26, 4: 2060-2075. Doi:10.1021\/acs.biomac.4c00609<\/li>\n\n\n\n<li class=\"ulux-list-item\">*Schneider, M. M., *Scheidt, T., *Priddey, A. J., *Xu, C. K., Hu, M., Meisl, G., Devenish, S. R. A., Dobson, C. M., Kosmoliaptsis, V. &amp; Knowles, T. P. J. (2023) Microfluidic antibody affinity profiling of alloantibody-HLA interactions in human serum. Biosens. Bioelectron. 228. DOI: 10.1016\/j.bios.2023.115196<\/li>\n\n\n\n<li class=\"ulux-list-item\">*Michels, J. J., Brzezinski, M., Scheidt, T., Lemke, E. A., &amp; Parekh, S. H. (2022) Role of Solvent Compatibility in the Phase Behavior of Binary Solutions of Weakly Associating Multivalent Polymers. Biomacromolecules 23, 1: 349-364. DOI: 10.1021\/acs.biomac.1c01301<\/li>\n\n\n\n<li class=\"ulux-list-item\">*Popper, B., Scheidt, T., &amp; Schieweck, R. (2021) RNA-binding protein dysfunction in neurodegeneration. Essays Biochem. 65, 7: 975-986. DOI: 10.1042\/EBC20210024<\/li>\n\n\n\n<li class=\"ulux-list-item\">*Scheidt, T., *Carozza, J. A., Kolbe, C. C., Aprile, F. A., Tkachenko, O., Bellaiche, M. M. J., Meisl, G., Peter, Q. A. E., Herling, T. W., Ness, S., Castellana- Cruz, M., Benesch, J. L. P., Vendruscolo, M., Dobson, C. M., Arosio, P., &amp; Knowles, T. P. J. (2021) The binding of the small heat-shock protein \u03b1Bcrystallin to fibrils of \u03b1-synuclein is driven by entropic forces. Proc. Natl. Acad. Sci. U.S.A. 118, 38. DOI: 10.1073\/pnas.2108790118<\/li>\n\n\n\n<li class=\"ulux-list-item\">*Kartanas, T., Levin, A., Toprakcioglu, Z., Scheidt, T., Hakala, T. A., Charmet, J., &amp; Knowles, T. P. J. (2021) Label-Free Protein Analysis Using Liquid Chromatography with Gravimetric Detection. Anal. Chem. 93, 5: 2848-2853. DOI: 10.1021\/acs.analchem.0c04149<\/li>\n\n\n\n<li class=\"ulux-list-item\">*Linse, S., Scheidt, T., Bernfur, K., Vendruscolo, M., Dobson, C. M., Cohen, S. I. A., Sileikis, E., Lundqvist, M., Qian, F., O&#8217;Malley, T., Bussiere, T., Weinreb, P. H., Xu, C. K., Meisl, G., Devenish, S. R. A., Knowles, T. P. J., &amp; Hansson, O. (2020) Kinetic fingerprints differentiate the mechanisms of action of anti-A\u03b2 antibodies. Nat. Struct. Mol. Biol. 27, 12: 1125-1133. DOI: 10.1038\/s41594-020-0505-6<\/li>\n\n\n\n<li class=\"ulux-list-item\">*Scheidt, T., *Kartanas, T., Peter, Q., Schneider, M. M., Saar, K. L., M\u00fcller, T., Challa, P. K., Levin, A., Devenish, S., &amp; Knowles, T. P. J. (2020) Multidimensional protein characterisation using microfluidic post-column analysis. Lab Chip 20, 2663- 2673. DOI: 10.1039\/D0LC00219D<\/li>\n\n\n\n<li class=\"ulux-list-item\">*Scheidt, T., \u0141api\u0144ska, U., Kumita, J. R., Whiten, D. R., Klenerman, D., Wilson, M. R., Cohen, S. I. A., Linse, S., Vendruscolo, M., Dobson, C. M., Knowles, T. P. J., &amp; Arosio, P. (2019) Secondary nucleation and elongation occur at different sites on Alzheimer\u2019s amyloid-\u03b2 aggregates. Sci. Adv. 5. DOI: 10.1126\/sciadv.aau3112<\/li>\n<\/ol>\n<\/div><\/section>\n<\/div>","protected":false},"excerpt":{"rendered":"","protected":false},"author":56,"featured_media":0,"parent":13079,"menu_order":0,"template":"","meta":{"featured_image_focal_point":[],"show_featured_caption":false,"ulux_newsletter_groups":"","uluxPostTitle":"Molecular Biophysics","uluxPrePostTitle":"Research Group","_trash_the_other_posts":false,"_price":"","_stock":"","_tribe_ticket_header":"","_tribe_default_ticket_provider":"","_tribe_ticket_capacity":"0","_ticket_start_date":"","_ticket_end_date":"","_tribe_ticket_show_description":"","_tribe_ticket_show_not_going":false,"_tribe_ticket_use_global_stock":"","_tribe_ticket_global_stock_level":"","_global_stock_mode":"","_global_stock_cap":"","_tribe_rsvp_for_event":"","_tribe_ticket_going_count":"","_tribe_ticket_not_going_count":"","_tribe_tickets_list":"[]","_tribe_ticket_has_attendee_info_fields":false},"field-of-interest":[290],"organisation":[],"authorship":[56],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v22.3 (Yoast SEO v22.3) - 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