{"id":476,"date":"2023-06-27T01:12:24","date_gmt":"2023-06-26T23:12:24","guid":{"rendered":"https:\/\/website.prod.unilu.spikeseed.cloud\/lcsb-en\/?post_type=research-groups&#038;p=476"},"modified":"2025-06-18T16:29:00","modified_gmt":"2025-06-18T14:29:00","slug":"molecular-functional-neurobiology","status":"publish","type":"research-groups","link":"https:\/\/www.uni.lu\/lcsb-en\/research-groups\/molecular-functional-neurobiology\/","title":{"rendered":"Molecular &amp; Functional Neurobiology"},"content":{"rendered":"<div class=\"section py-0 static\"><div class=\"section py-0 section wp-block-unilux-blocks-navigation-and-hero py-0\">\n    \n<div class=\"wp-block-unilux-blocks-wrapper container xl:max-w-screen-xl\"><div class=\"js-secondary-nav--sticky wp-block-unilux-blocks-secondary-navigation\" id=\"9c9bccda-a622-4aae-a789-e3dfd6c1ac6c\">\n    <nav\n        id=\"secondary-navigation\"\n        role=\"navigation\"\n        aria-label=\"Secondary menu\"\n        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<\/a>\n<\/li>\n<li class=\"secondary-nav__item\">\n    <a\n        href=\"https:\/\/www.uni.lu\/lcsb-en\/research-groups\/molecular-functional-neurobiology\/publications\/\"\n        target=\"\"\n        rel=\"noreferrer noopener\"\n        class=\"secondary-nav__link \"\n            >\n        <svg aria-hidden=\"true\" focusable=\"false\" class=\"icon icon-outline icon--xs\">\n            <use xlink:href=\"https:\/\/www.uni.lu\/wp-content\/themes\/unilux-theme\/assets\/images\/icons\/icons-outline.svg#icon--arrow-right\" \/>\n        <\/svg>\n        <span class=\"secondary-nav__name\">Publications<\/span>\n    <\/a>\n<\/li>\n<li class=\"secondary-nav__item\">\n    <a\n        href=\"https:\/\/www.uni.lu\/lcsb-en\/research-groups\/molecular-functional-neurobiology\/people\/\"\n        target=\"\"\n        rel=\"noreferrer noopener\"\n        class=\"secondary-nav__link \"\n            >\n        <svg aria-hidden=\"true\" focusable=\"false\" class=\"icon icon-outline icon--xs\">\n            <use xlink:href=\"https:\/\/www.uni.lu\/wp-content\/themes\/unilux-theme\/assets\/images\/icons\/icons-outline.svg#icon--arrow-right\" \/>\n        <\/svg>\n        <span class=\"secondary-nav__name\">People<\/span>\n    <\/a>\n<\/li>\n        <\/ul>\n    <\/nav>\n<\/div>\n<\/div>\n\n<div class=\"wp-block-unilux-blocks-wrapper max-w-screen-3xl mx-auto section py-0\">\n<section class=\"section no-padding-y wp-block-unilux-blocks-hero\">\n    <div class=\"hero hero--2 hero--overlay-top hero--overlay-bottom\">\n        \n<header class=\"wp-block-unilux-blocks-wrapper hero__header\">\n<div class=\"wp-block-unilux-blocks-wrapper hero__container\">\n<span class=\"hero__title__subject wp-block-unilux-blocks-plain-text\"><\/span>\n\n\n<h1 class=\"has-text-align-left wp-block-unilux-blocks-heading\"        id=\"deciphering-molecular-underpinnings-of-parkinsons-disease\"\n    >\nDeciphering molecular underpinnings of Parkinson\u2019s disease<\/h1>\n<\/div>\n<\/header>\n<figure class=\"wp-block-dev4-reusable-blocks-image hero__visual object-fit--cover\">\n    \n<img decoding=\"async\" class=\"wp-block-image unilux-custom-image-block\"\n                alt=\"\"\n            src=\"https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/6\/2023\/06\/LCSB_Molecular-Functional-Neurobiology_overview_1.jpg\"\n                srcset=\"https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/6\/2023\/06\/LCSB_Molecular-Functional-Neurobiology_overview_1-300x173.jpg 300w, https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/6\/2023\/06\/LCSB_Molecular-Functional-Neurobiology_overview_1-768x442.jpg 768w, https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/6\/2023\/06\/LCSB_Molecular-Functional-Neurobiology_overview_1.jpg 825w\"\n                style=\"object-position: 50.00% 50.00%; font-family: &quot;object-fit: cover; object-position: 50.00% 50.00%;&quot;; aspect-ratio: 16\/9; object-fit: cover; width: 100%;\"\n        loading=\"lazy\"\n\/>    <\/figure>\n<div class=\"wp-block-unilux-blocks-wrapper hero__body\">\n<div class=\"wp-block-unilux-blocks-wrapper hero__container\">\n<p class=\"wp-block-unilux-blocks-plain-text\">The Molecular &amp; Functional Neurobiology group, led by Prof. Anne Gr\u00fcnewald, studies genetic and non-genetic causes of neurodegeneration in Parkinson\u2019s disease.<\/p>\n\n\n<ul class=\"wp-block-unilux-blocks-custom-buttons btn-list\">\n\n<\/ul>\n<\/div>\n<\/div>\n    <\/div>\n<\/section><\/div>\n<\/div>\n\n<section class=\"section section wp-block-unilux-blocks-content-free-media-and-statistics\">\n    \n<div class=\"wp-block-unilux-blocks-wrapper container xl:max-w-screen-xl\">\n<h2 class=\"has-text-align-left wp-block-unilux-blocks-heading\"        id=\"a-glimpse-into-our-research\"\n    >\nA glimpse into our research<\/h2>\n\n\n\n<div class=\"wp-block-unilux-blocks-wrapper flex flex-wrap lg:-mx-32\">\n<div class=\"wp-block-unilux-blocks-wrapper w-full lg:w-7\/12 lg:order-2 lg:px-32\">\n<section class=\"wp-block-unilux-blocks-image-video-wrapper\">\n    <div class=\"thumbnail  wp-block-unilux-blocks-thumbnail-video\">\n    <div class=\"card bg-theme p-0\">\n        <div class=\"card__container p-0\">\n            <div class=\"card__body p-0\">\n                <iframe \n            src=\"https:\/\/www.youtube.com\/embed\/8GLm4nzgcrU\" \n            title=\"YouTube video player\" \n            allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" \n            style=\"object-position: 50% 50%; aspect-ratio: 16\/9; object-fit: cover; width: 100%;\"\n            allowfullscreen data-cookieconsent=\"ignore\">\n            <\/iframe>                            <\/div>\n        <\/div>\n    <\/div>\n<\/div>\n<\/section><\/div>\n\n\n\n<div class=\"wp-block-unilux-blocks-wrapper w-full lg:w-5\/12 lg:order-1 lg:px-32 self-center\">\n<h3 class=\"has-text-align-left wp-block-unilux-blocks-heading\"    >\n<\/h3>\n\n\n\n<p>We explore the role of the mitochondrial genome in idiopathic Parkinson\u2019s disease. Our aim is to identify cellular pathways, which may be targeted for therapeutic intervention. For monogenic Parkinsonism, we aim to understand why some individuals do not manifest any signs of the disease despite the presence of a mutation. We want to uncover mechanisms that could be modulated to delay the onset.<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-unilux-blocks-wrapper w-full lg:w-7\/12 lg:order-4 lg:px-32\">\n<div class=\"wp-block-unilux-blocks-wrapper flex flex-col mt-[1.5rem]\">\n<div class=\"wp-block-unilux-blocks-wrapper lg:ml-auto\">\n<h3 class=\"has-text-align-left wp-block-unilux-blocks-heading\"    >\n<\/h3>\n\n\n<ul class=\"flex flex-wrap mb-24 -mx-32 wp-block-unilux-blocks-facts-figures-horizontal\">\n    <li class=\"wp-block-unilux-blocks-facts-figures-item\">\n    \n<div class=\"wp-block-unilux-blocks-wrapper figure-stats\">\n<div class=\"figure-stats__value text-theme wp-block-unilux-blocks-plain-text\"><\/div>\n\n\n<div class=\"figure-stats__description wp-block-unilux-blocks-plain-text\"><\/div><\/div>\n<\/li><\/ul>\n\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-unilux-blocks-wrapper w-full lg:w-5\/12 lg:order-3 lg:px-32\">\n<ul class=\"wp-block-unilux-blocks-quick-link-underline\">\n    \n<li class=\"wp-block-unilux-blocks-quick-link-underline-item\">\n    <a\n            href=\"https:\/\/www.uni.lu\/lcsb-en\/research-groups\/molecular-functional-neurobiology\/research\/\"\n            class=\"wp-block-unilux-blocks-anchor\"        target=\"\"\n>\n    \n<span class=\"hero__title__subject wp-block-unilux-blocks-plain-text\">Research<\/span><svg aria-hidden=\"true\" focusable=\"false\" class=\"icon icon-outline icon--arrow-right \"><use xlink:href=\"https:\/\/www.uni.lu\/wp-content\/themes\/unilux-theme\/assets\/images\/icons\/icons-outline.svg#icon--arrow-right\"><\/use><\/svg><\/a>\n<\/li>\n\n<li class=\"wp-block-unilux-blocks-quick-link-underline-item\">\n    <a\n            href=\"https:\/\/www.uni.lu\/lcsb-en\/research-groups\/molecular-functional-neurobiology\/publications\/\"\n            class=\"wp-block-unilux-blocks-anchor\"        target=\"\"\n>\n    \n<span class=\"hero__title__subject wp-block-unilux-blocks-plain-text\">Publications<\/span><svg aria-hidden=\"true\" focusable=\"false\" class=\"icon icon-outline icon--arrow-right \"><use xlink:href=\"https:\/\/www.uni.lu\/wp-content\/themes\/unilux-theme\/assets\/images\/icons\/icons-outline.svg#icon--arrow-right\"><\/use><\/svg><\/a>\n<\/li>\n\n<li class=\"wp-block-unilux-blocks-quick-link-underline-item\">\n    <a\n            href=\"https:\/\/www.uni.lu\/lcsb-en\/research-groups\/molecular-functional-neurobiology\/people\/\"\n            class=\"wp-block-unilux-blocks-anchor\"        target=\"\"\n>\n    \n<span class=\"hero__title__subject wp-block-unilux-blocks-plain-text\">People<\/span><svg aria-hidden=\"true\" focusable=\"false\" class=\"icon icon-outline icon--arrow-right \"><use xlink:href=\"https:\/\/www.uni.lu\/wp-content\/themes\/unilux-theme\/assets\/images\/icons\/icons-outline.svg#icon--arrow-right\"><\/use><\/svg><\/a>\n<\/li>\n<\/ul><\/div>\n\n\n\n<div class=\"wp-block-unilux-blocks-wrapper w-full lg:w-5\/12 lg:order-5 lg:px-32\">\n<ul class=\"wp-block-unilux-blocks-custom-buttons btn-list\"><\/ul>\n<\/div>\n<\/div>\n<\/div>\n<\/section>\n\n\n<section class=\"py-0 wp-block-unilux-blocks-free-section section\"><div class=\"container xl:max-w-screen-xl\">\n<h2 class=\"has-text-align-left wp-block-unilux-blocks-heading\"        id=\"news\"\n    >\nNews<\/h2>\n\n\n\n<ul class=\"wp-block-unilux-blocks-news-card-group flex flex-wrap -mx-16\"><li class=\"w-full sm:w-1\/2 px-16 w-full px-16 sm:w-1\/2  wp-block-unilux-blocks-news-card\">\n    <div class=\"ulux-card card-news bg-theme\">\n        <div class=\"ulux-card__container\">\n            <div class=\"ulux-card__visual\">\n                <img decoding=\"async\" class=\"w-full\" src=\"https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/6\/2023\/07\/Federal-President-Steinmeier-and-HRH-Grand-Duke-Henry-visit-the-LCSB_feature-300x300.png\" srcset=\"https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/6\/2023\/07\/Federal-President-Steinmeier-and-HRH-Grand-Duke-Henry-visit-the-LCSB_feature-768x767.png 768w, https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/6\/2023\/07\/Federal-President-Steinmeier-and-HRH-Grand-Duke-Henry-visit-the-LCSB_feature-300x300.png 300w, https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/6\/2023\/07\/Federal-President-Steinmeier-and-HRH-Grand-Duke-Henry-visit-the-LCSB_feature-1024x1024.png 1024w, https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/6\/2023\/07\/Federal-President-Steinmeier-and-HRH-Grand-Duke-Henry-visit-the-LCSB_feature-150x150.png 150w, https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/6\/2023\/07\/Federal-President-Steinmeier-and-HRH-Grand-Duke-Henry-visit-the-LCSB_feature.png 1500w\" sizes=\"(max-width: 768px) 100vw, 768px\" alt=\"\" \/>\n            <\/div>\n\n            <div class=\"ulux-card__body\">\n                <h3 class=\"ulux-card__title break-words\">Federal President Steinmeier and HRH Grand Duke Henry visit the LCSB<\/h3>\n                <div class=\"ulux-card__category break-words\">Outreach<\/div>\n                <time class=\"ulux-card__date break-words\"\n                        datetime=\"2023-07-12\">12 July 2023<\/time>\n                <div class=\"ulux-card__topic break-words\">Life Sciences &amp; Medicine<\/div>\n                <a class=\"ulux-card__link link-text link-absolute\"\n                    href=\"https:\/\/www.uni.lu\/lcsb-en\/news\/federal-president-steinmeier-and-hrh-grand-duke-henry-visit-the-lcsb\/\"\n                    target=\"\">\n                    <span class=\"link-text__name\">Learn more<\/span>\n                    <svg aria-hidden=\"true\" focusable=\"false\" class=\"icon icon-outline icon--arrow-right icon--2xs\"><use xlink:href=\"https:\/\/www.uni.lu\/wp-content\/themes\/unilux-theme\/assets\/images\/icons\/icons-outline.svg#icon--arrow-right\"><\/use><\/svg>                <\/a>\n            <\/div>\n        <\/div>\n    <\/div>\n<\/li>\n<\/ul>\n<\/div><\/section>\n\n\n\n<section class=\"wp-block-unilux-blocks-free-section section\"><div class=\"container xl:max-w-screen-xl\">\n<h2 class=\"has-text-align-left wp-block-unilux-blocks-heading\"        id=\"this-research-group-is-part-of\"\n    >\nThis research group is part of<\/h2>\n\n\n\n<ul class=\"wp-block-unilux-blocks-button-list-v2\">\n<li class=\"wp-block-unilux-blocks-button-list-item-v2\"><a class=\"quick-link\" href=\"https:\/\/www.uni.lu\/lcsb-en\/\" target=\"\" role=\"link\" rel=\"noopener\" tabindex=\"0\"><span class=\"quick-link__container\">\n<div class=\"wp-block-unilux-blocks-block-inserter quick-link__img\"><figure class=\"wp-block-dev4-reusable-blocks-image  object-fit--cover\">\n    \n<img decoding=\"async\" class=\"wp-block-image unilux-custom-image-block\"\n                alt=\"Luxembourg Centre for Systems Biomedicine Logo\"\n            src=\"https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/6\/2023\/06\/uni-centre-lcsb-no-baseline.svg\"\n                    style=\"object-position: 50.00% 50.00%; font-family: &quot;object-fit: cover; object-position: 50.00% 50.00%;&quot;; aspect-ratio: 1\/1; object-fit: cover; width: 100%;\"\n        loading=\"lazy\"\n\/>    <\/figure><\/div>\n\n\n\n<span class=\"quick-link__name wp-block-unilux-blocks-plain-text\">Luxembourg Centre for Systems Biomedicine (LCSB)<\/span>\n\n<svg aria-hidden=\"true\" focusable=\"false\" class=\"icon icon-outline icon--arrow-right \"><use xlink:href=\"https:\/\/www.uni.lu\/wp-content\/themes\/unilux-theme\/assets\/images\/icons\/icons-outline.svg#icon--arrow-right\"><\/use><\/svg><\/span><\/a><\/li>\n<\/ul>\n\n\n<div class=\"wp-block-unilux-blocks-spacer is-spacer-size-lg\"><\/div><\/div><\/section>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>The Molecular &amp; Functional Neurobiology group, led by Prof. Anne Gr\u00fcnewald, studies genetic and non-genetic causes of neurodegeneration in Parkinson\u2019s disease.<\/p>\n","protected":false},"author":39,"featured_media":478,"parent":0,"menu_order":0,"template":"","meta":{"featured_image_focal_point":[],"show_featured_caption":false,"ulux_newsletter_groups":"","uluxPostTitle":"Molecular & Functional Neurobiology","uluxPrePostTitle":"Research 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